A concise flow synthesis of indole-3-carboxylic ester and its derivatisation to an auxin mimic
An assembled suite of flow-based transformations have been used Machine Quilting to rapidly scale-up the production of a novel auxin mimic-based herbicide which was required for preliminary field trials.The overall synthetic approach and optimisation studies are described along with a full description of the final GY6.35 led M75 reactor configurati